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Dr. Rosemary Jagus

  • JagusR

    PROJECT DIRECTOR (UMCES - IMET)

    Associate Professor, IMET
    University of Maryland Center for Environmental Science (UMCES)

    Phone: (410) 234 8822 | Email: jagus@umces.edu | Fax: (410) 234 8896


    Website 


    USM Elkins Professor of Marine Biotechnology, Institute of Marine and Environmental Technology, UMCES, Baltimore, MD, 2017-present


    EDUCATION


    University College London (1976)
    Ph.D., Biochemistry
    University College of North Wales (1971)
    M.S., Zoology

    RESEARCH INTERESTS

    1. Translational control of gene expression
    2. Regulation of gene activity during early development
    3. Host defense against virus infection and viral countermeasures
    4. Diversity of eukaryotic translational initiation with emphasis on dinoflagellates. 

    SELECTED PUBLICATIONS

    1. Gillespie, K, Joshi, B & Jagus, R. (2019). Comparison of Class I and III eIF4E family members in zebrafish (Danio rerio), Int. Journal Molecular Sciences, In press.
    2. Liu, CL, Dasi, E, Place, AR & Jagus, R. (2019). eIF2α phosphorylation in response to nutrient deficiency and other stressors in ZFL cells, PlosOne, In press.
    3. Chung, JS, Huang, X, Bachvaroff, TB, Lawrence, A, Pitula, JS & Jagus, R. (2019). Reovirus infection changes transcript levels of eukaryotic translation initiation factor 4E (eIF4E) family members and the eIF4E binding protein (4E-BP) in the blue crab, Callinectes sapidus, Journal of Shellfish Res, In press. 
    4. Roy, S, Jagus, R. & Morse, D. (2018). Translation and Translational Control in Dinoflagellates. Microorganisms, 6(2). pii: E30. doi: 10.3390/microorganisms6020030.
    5. Liu, CL, Watson, A.M., Place, A.R & Jagus, R. (2017). Effects of taurine supplementation on cell growth, amino acid pools and expression of the taurine biosynthetic pathway and transporter genes in a fish cell line (ZFL), Marine Drugs: Advances and New Perspectives in Marine Biotechnology II, 15(6): E147. doi: 10.3390/md15060147.
    6. Liu, CL, Place, A.R & Jagus, R. (2017). Use of antibiotics for maintenance of axenic cultures of Amphidinium carterae for the analysis of translation, Marine Drugs: Advances and New Perspectives in Marine Biotechnology II, 15(8): E242. doi: 10.3390/md15080242.
    7. Hernández, G, Gillespie, KM, Bachvaroff, TB, Jagus, R, Igreja, C, Peter, D, Bulfoni, M, & Cosson, B. (2016). Evolution of eIF4E-interacting proteins. In Evolution of the Protein Synthetic Machinery and its Regulation, eds. Hernandez, G. and Jagus, R. SpringerVerlag, pp 165-186.
    8. Gillespie, KM, Bachvaroff, TB, & Jagus, R. (2016). Expansion of eIF4E and 4EBP family members in deuterostomes. In Evolution of the Protein Synthetic Machinery and its Regulation, eds. Hernandez, G. and Jagus, R. Springer-Verlag, pp 207-234.
    9. Hernandez, G. & Jagus, R. co-editors (2016). Evolution of the Protein Synthetic Machinery and its Regulation, Springer-Verlag, Switzerland.
    10. Jones, G. D., Williams, E., Place, A. R., Jagus, R. & T.R. Bachvaroff, (2015). Dinoflagellate eIF4E diversity: a custom toolkit for translational control. BMC Evolutionary Biology, 15:14.
    11. Jones, G. D., Williams, E. P., Place, A. R., Bachvaroff, T. R., & Jagus, R. (2015). New tools in the Karlodinium veneficum translation initiation toolbox, Proceedings of the 16th International Conference on Harmful Algae, Cawthron Institute, Nelson, New Zealand and the International Society for the Study of Harmful Algae (ISSHA) A. Lincoln MacKenzie [Ed], 237-240, 2015.
    12. Bachvaroff, T. R., Williams, E., Jagus, R., & Place, A.R. (2015) A noncryptic noncanonical multi-module PKS/NRPS found in dinoflagellates, Proceedings of the 16th International Conference on Harmful Algae, Cawthron Institute, Nelson, New Zealand and the International Society for the Study of Harmful Algae (ISSHA) A. Lincoln MacKenzie [Ed], 101-104.
    13. Williams, E., Place, A. R., & Jagus, R. (2015).  Discovery of non-coding small RNAs in Amphidinium carterae differentially expressed over a diel cycle. Proceedings of the 16th International Conference on Harmful Algae, Cawthron Institute, Nelson, New Zealand and the International Society for the Study of Harmful Algae (ISSHA) A. Lincoln MacKenzie [Ed], 233-236.

    BIOSKETCH


    Dr. Rosemary Jagus received her Ph.D. in Biochemistry from University College London in 1976.  She studies the regulation of protein synthesis in eukaryotic organisms from protists to zebrafish.  She is working currently on the role of phosphorylation of the translational initiation factor eIF2 in the adaptation of fish to different diets, changing temperatures, and viral infection.  

    In addition, Dr. Jagus is studying the translational regulation of gene expression in toxic dinoflagellates, as well as the diversity of the translational machinery in protists. She is currently USM Elkins Professor of Marine Biotechnology (from 2017-present) and also the coordinator of the LMRCSC summer internship program at UMCES IMET. 

     



  • NOAA Living Marine Resources Cooperative Science Center
    University of Maryland Eastern Shore (Lead Institution)
    (410) 651-7870
    Award numbers: FY 2016 Award #NA16SEC4810007 
    Funding Agency: NOAA Educational Partnership Program with Minority-Serving Institutions (EPP/MSI)
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