Miguel Martin, PhD
Professor, Pharmaceutical Sciences
Education
- Ph.D.- Physiology (2000) University of Alberta,
Edmonton, Alberta, Canada
- M.S.- Medicine (1995) Memorial University of
Newfoundland, St. John’s, Canada
- B.S. (Honors)- Biophysics (1991) Moscow State
University, Moscow, Russia
Bio
After completing his postdoctoral
training at the University of Houston in 2003, Dr. Martin joined the faculty at
the University of Vermont where he taught several undergraduate and graduate
courses, including a capstone Physiology course and a Neurodevelopment
course for Biology majors. At the University of Vermont, Dr. Martin mentored
the research thesis of three PhD and one MSc student. He was also actively
involved in undergraduate research.
Dr. Martin’s main research interest
is in neurophysiology, particularly the role of ion channels in cell
physiology. His research has focused on the function of voltage-gated calcium
channels and calcium-permeable receptors during neuronal cell differentiation
and cancer development. Using the chicken embryo as a model, he has studied the
function of T-type calcium channels and calcium-permeable AMPA receptors during
neuronal cell differentiation. He is currently investigating the functional
implications of T-type calcium channel expression in prostate cancer development.
Dr. Martin’s research has been supported by grants from the National Institute
of Health and the Vermont Genetic Network. During his professional career, Dr.
Martin has co-authored many scientific articles in neuroscience, physiology and
neurodevelopment. He has conducted multiple presentations at national and
international meetings. Dr. Martin is a member of the Society for Neuroscience,
the American Physiological Society, the American Association for Cancer
Research, and the American Association of College of Pharmacy.
Courses Taught
PHAR 511 Genetic Control of Cell Function
PHAR 520 Principles of Neurobiology and Neuropharmacology
PHAR 521 Cardiovascular and Renal Pharmacology and Med. Chemistry
PHAR 522 Gastrointestinal and Genitourinary Pharmacology and
Med. Chemistry
PHAR 525 Neuropharmacology and Medicinal Chemistry
Scholarly activities
Zhang
QJ, Hsia SC, Martin-Caraballo M
(2017) Regulation of T-type Ca2+ channel expression by herpes
simplex virus-1 infection in sensory-like ND7 cells.
J. Neurovirol. http://link.springer.com/article/10.1007/s13365-017-0545-9
Greer JJ, Martin-Caraballo
M (2017) Developmental plasticity of
phrenic motoneurons and diaphragm properties with the insertion of inspiratory
drive transmission in uterus. Exp. Neurol. 287(Pt 2):
137-143.
Weaver
EM, Zamora FJ, Hearne JL, Martin-Caraballo M (2015) Posttranscriptional
regulation of T-type Ca2+ channel expression by interleukin-6 in
prostate cancer cells. Cytokine 76(2): 309-320.
Weaver
EM, Zamora FJ, Puplampu-Dove YA, Kiessu E, Hearne JL, Martin-Caraballo M (2015)
Regulation
of T-type calcium channel expression by sodium butyrate in prostate cancer
cells.
Eur J Pharmacol. 749: 20-31.
Yoon
YJ, White SL, Ni X, Gokin AP, Martin-Caraballo
M (2012) Downregulation of
GluA2 AMPA receptor subunits reduced the dendritic arborization of developing
spinal motoneurons. PLoS ONE
7(11): e49879. http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0049879
Ni X, Martin-Caraballo M (2010) Differential
effect of glutamate receptor activation on the maturation of dendritic
morphology in lumbar motoneurons. Neuropharmacol. 58: 593-604.
Click here for the list of articles
on https://www.ncbi.nlm.nih.gov/pubmed/?term=martin-caraballo
Areas of Interest and/or Experience
- Ion channel physiology
- Regulation of ion channel expression in prostate cancer
- Regulation of intracellular calcium by calcium channels
Current Research Activities
Role of T-type calcium channels in
the progression of prostate cancer
Regulation of T-type calcium channel expression by herpes virus infection