Ali B. Ishaque, Ph.D.

  •  
    Associate Professor 
    Department of Natural Sciences 
    Email:  abishaque@umes.edu
    Phone: 410-651-6050; Fax 410-651-7739



    Education:

    • Ph.D. in Ecotoxicology, Free University of Brussels, Belgium
    • M.S. in Marine Ecology, Free University of Brussels, Belgium
    • B.S. in Chemistry, University of Science & Technology, Ghana


    Professional Experience:

    • Associate Professor (tenured), Environmental Science, University of Maryland Eastern Shore, 2005-present
    • Assistant Professor, Environmental Science, University of Maryland Eastern Shore, 2003-2005
    • Lecturer, Environmental Science, University of Maryland Eastern Shore, 2001-2003
    • Postdoctoral Fellow, Jackson State University, Jackson, MS, 1999-2001
    • Postdoctoral Fellow, Free University of Brussels, Belgium, 1998-1999
    • Research Associate, Free University of Brussels, Belgium, 1992-1998

    Publications:

    • I.B. Ali, C.R. Joiris, L. Holsbeek (1997). Total and Organic Mercury in the Polychaete Maldanes sarsi and the Starfish Ctenodiscus crispatus from the Barents Sea. Sci. Tot.  Environ 201: 189-194.

    • I. B. Ali, C.R. Joiris, L. Holsbeek (1997). Polychlorinated Biphenyls in Barents and Greenland Seas Fish. Bull. of Environ.  Contam. And Toxicol. 58: 885-892.

    • L.Holsbeek, C.R. Joiris, V. Debacker, I.B. Ali, P. Roose, JN. Nellissen, S. Gobert, JM. Bouquegneau and M. Bossicart (1999). Heavy Metals, Organochlorines and Polycyclic Aromatic Hydrocarbons in Sperms Whales Stranded in the Southern North Sea during the 1994/1995 winter. Mar. Poll. Bull 38:304-313.

    • P.B. Tchounwou, B. Wilson and A. Ishaque (1999). Important Considerations in the Development of Public Health Advisories for Arsenic and Arsenic-Containing Compounds in Drinking Water. Review on Environ. Health. 14 (4): 211-229.

    • P.B. Tchouwnou, B. A. Wilson, A. B. Ishaque and D. Sutton (2000). Toxicity evaluation of Arsenic Trioxide and Atrazine to Three Developmental Stages of Japanese Medaka (Oryzias latipes). In Metal Ions in Biology and Medicine. J.A. Centeno, Ph. Collery, G. Vernet, R.B. Finkelman H. Gibb, J.C. Etienne (Eds) 6:18-20

    • P.B. Tchouwnou, B. A. Wilson, A. B. Ishaque,  J. Schneida, (2001). Transcriptional activation of stress genes, and cytotoxicity in human liver carcinoma cells (HepG2) exposed to 2,4,6- Trinitrotoluene, 2,4-Dinitrotoluene, and 2,6- Dinitrotoluene. Environmental Toxicology 16: 209-216.

    • P.B. Tchounwou, B. Wilson and A. Ishaque (2001). Embryotoxicity of Arsenic Trioxide and Atrazine to Japanese Medaka (Oryzias latipes), and Cytotoxicity to Human Liver Cells (HepG2). Environmental Toxicology and Risk Assessment: Science, Policy and Standardization – Implications for Environmental Decisions: Tenth Volume, ASTM STP 1403: 83-95. 

    • P.B. Tchouwnou, B. A. Wilson, A. B. Ishaque, and J. Schneider (2001). Atrazine Potentiation of Arsenic Trioxide-Induced Cytotoxicity and Gene Expression in Human Liver Carcinoma Cells (HepG2). Molecular and Cellular Biochemistry 222:49-59.

    • P.B. Tchouwnou, A. B. Ishaque, and J. Schneider (2001). Cytotoxicity and Transcriptional Activation of Stress Genes in Human Liver Carcinoma Cells (HepG2) Exposed to Cadmium Chloride. Molecular and Cellular Biochemistry 222:21-28

    • P.B. Tchouwnou, A. B. Ishaque, and E. Shen (2001). Cytotoxicity and Stress Genes in Human Liver Carcinoma Cells (HepG2) Exposed to Lead Nitrate. Special Issue, Abstracts of the IXth International Congress of Toxicology, 8-12 July, 2001- Brisbane, Australia. Vol. 164 nos. 1-3: 65. Guest Editor: P.F.A Wright.

    • Rowshan A. Begum, Ibrahim O. Farah, Ali B. Ishaque  (2002). Pifithrin-a (PFT-a) caused differential protection of rat liver cells and hepg2 cell line in response to the selective cytotoxicity of arsenic and cadmium. Biomedical Sciences Instrumentation. 38:41-46

    • P.B. Tchouwnou, A. B. Ishaque, D. Sutton, Nanuli Ninashvili and Elaine Shen (2002). Biomarkers of Sensitivity and effect associated with cadmium and mercury toxicityin human liver carcinoma (HepG2) cells. In Metal Ions in Biology and Medicine. L. Khassanova, Ph. Collery, I. Maymard, Z. Khassanova, J.C. Etienne (Eds) 7:132-137.

    • Waneene C. Dorsey, Paul B. Tchounwou, Ali B. Ishaque, and Elaine Shen (2002). Transcriptional Activation of Stress Genes and Cytotoxicity in Human Liver Carcinoma (HepG2) Cells Exposed to Pentachlorophenol Int. J. Mol. Sci. 3, 992-1007.

    • Paul B. Tchounwou, Cecilia Newsome, Konsuela Glass, Jose A. Centeno, Jerzy Leszczynski, Joseph Bryant, Joseph Okoh, Ali Ishaque, and Marius Brow (2003) Environmental Toxicology and Health Effects Associated with Dinitrotoluene Exposure. Review on Environ. Health Vol 18:3, 203-229.

    • Ali B. Ishaque, Paul B. Tchounwou, Barbara A. Wilson and Teresa Washington (2004) Developmental arrest in Japanese medaka (Oryzias latipes) embryos exposed to sublethal concentrations of atrazine and arsenic trioxide; Journal of Environmental Biology  25:1, 1-6

    • Paul B. Tchounwou, Clement G. Yedjou, Dominique N. Foxx, Ali B. Ishaque, Elaine Shen (2004). Lead-induced cytotoxicity and transcriptional activation of stress genes in human liver carcinoma (HepG2) cells. Molecular and Cellular Biochemistry 255:161-170.

    • Ali B. Ishaque, Christine Timmons, Frederick V. Ballard, Carine Hupke, Kalpana Dulal, Linda R. Johnson, Tonya M. Gerald, Dwayne Boucaud, Paul B. Tchounwou (2005). Cytotoxicity of Dinitrotoluenes (2,4-DNT, 2,6-DNT ) to MCF-7 and MRC-5 Cells Int. J. Environ. Res. Public Health  2(2), 304-307

    • Ali B. Ishaque, Eugene L. Bass, Roman Jesien, Steven Hughes, and Carine Hupke (2005) A better method for standardizing vitellogenin content of fish tissue;  Journal of Environmental Biology 26 (1) 1-5
    • Ali B. Ishaque, Linda R. Johnson, Tonya M. Gerald, Dwayne Boucaud, Joseph Okoh, Paul B. Tchounwou (2006). Assessment of Individual and Combined Toxicities of Four Non-Essential Metals (As, Cd, Hg and Pb) in the Microtox.  Int. J. Environ. Res. Public Health 3 (1) 118-120.
    • Farah IO, Begum RA, Ishaque AB (2007). Differential protection and transactivation of P53, P21, Bcl2, PCNA, cyclin G, and MDM2 genes in rat liver and the HepG2 cell line upon exposure to pifithrin. Biomed Sci Instrum 43 : 116-21. 

    • Ali B. Ishaque and Tito I. Aighewi (2008). Dose-Response. In Sven Erik Jergensen and Brian D. Fath    (Editor-in-Chief), Ecotoxicology. Vol [2] of Encyclopedia of Ecology, 5 vols. Pp. [957-967]    Oxford:  Elsevier.
    • Charles K. Klutse, Mack Kelly; Squibb, Katherine, Ishaque, Ali (2009). Differential toxicological interaction among arsenic, cadmium, lead and mercury on MCF 7 cell line. Scholarly Research Exchange, Volume 2009 • Article ID 789636 • doi:10.3814/2009/789636
    • NOSAKHARE, O.K.; AIGHEWI, I.T.; CHI, A.Y.; ISHAQUE, A.B., and MBAMALU, G., 2012. Land use land cover changes in the lower Eastern Shore watersheds and coastal bays of Maryland: 1986–2006. Journal of Coastal Research, 28(1A), 54–62. West Palm Beach (Florida), ISSN 0749-0208

    • Aighew, I.T.,Osarodion K. Nosakhare  and Ali B. Ishaque 2012. Land Use-Land Cover Changes and Sewage Loading in the Lower Eastern Shore Watersheds and Coastal Bays of Maryland: Implications for Water Quality. Journal of Coastal Research; doi: 10.2112/JCOASTRES-D-11-00195.1. 

    • Egbe Egiebor, Adam Tulu, Nadia Abou-Zeid, Isoken Aighewi and Ali Ishaque 2013. The Kinetic Signature of Toxicity of Four Heavy Metals and Their Mixtures on MCF7 Breast Cancer Cell Line
      Int. J. Environ. Res. Public Health 201310(10), 5209-5220;  doi:10.3390/ijerph10105209;    http://www.mdpi.com/1660-4601/10/10/5209/

    Professional Affiliations:

    • Member of the American Association for the Advancement of Science (AAAS)
    • Editorial Board Member, Journal of Marine Science: Research & Development- Open Access
    • Active Member Society of Toxicology
    • Member American Association for Cancer Research (AACR)

    Awards:

    • 2009 AACR Minority –Serving  Institution  Faculty Scholar in Cancer Research Award
    • 2011 AACR Minority –Serving  Institution  Faculty Scholar in Cancer Research Award

    Courses:

    • Principles of Environmental Sciences
    • Marine Ecotoxicology
    • Independent  study
    • Undergraduate  Research
    • Senior seminar
    • MS thesis
    • Doctoral dissertation